Receptors (brain)

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Anecdotal observations by John Thomas

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Brain receptors: receive messages informing the body of the status of various organs and tissues using various pathways i.e. nerve signals, messenger hormone signaling molecules, etc. and uses these message/signals to turn organs on/off and to increase/decrease activity already initiated.


This discussion is limited to discussion of insulin, leptin and adrenaline resistance.

When brain receptors become glazed-over (glazed) they lose the ability to properly measure and respond to incoming signal molecules from organs, tissues and cells.

In the case of leptin resistance, leptin is made by fat cells as a signalling molecule to tell the brain what it should do about incoming food.  Responses are: 1. store the food energy as body fat, or 2. burn the food and produce energy to operate the system.

Glazing of brain receptors affects everyone, sooner or later; age is not the determining factor.  For example, children with ADD or ADHD, autism and Asperger’s, as well as older people with Alzheimer’s, Parkinson’s and severe brain fog.

Poor cognitive function involves plaque formation of the brain. Age is not the determining factor in loss of cognitive function; rather, hormone resistance and dysfunction of the pancreas either because of incorrect instructions (or lack of them) from the brain, or pancreatic burn-out or inability to respond to correct brain signals.

Brain plaque is another name for varnishing of leptin brain receptors.  Leptin is produced by fat cells to tell the brain what it should or should not instruct the pancreas to do i.e. turn on and release insulin, or, turn off and release none.

The pancreas controls insulin production which is orchestrated by brain receptor recognition of your leptin levels.   As receptors glaze-over from sugar-based plaque, the ability to restore balance is lost; then you become pre-diabetic, then diabetic.

Notice the words sugar-based plaque/varnish?  The point is formation of this disruptive substance on leptin brain receptors comes from elevated blood sugar levels. So-called normal blood sugar levels are 20-40 points too high because of sugar/carbohydrate intake in the face of insufficient dietary fat.

Think of poor brain receptor recognition of leptin signals for what it is; a condition of inflammatory aging; a symptom of pre-diabetes and/or diabetes type 1 and diabetes type 2, as well as diabetes type 3.

Systemic, low-grade inflammation is the PRIMARY driver of aging and dis-eases from cancer and cardiovascular to arthritis and diabetes.  Syndromes and disorders are side effects of pre-diabetes and diabetes type 3.  In other words, inflammation drives everything!

Read Autoimmune Attack Cycle and the Sugar/Alcohol Cycle. Click hyperlinks to access the information.

Read Special Insights, Pre-Diabetes & Aging in Archive link below.


  1. Change your lifestyle and your diet.
  2. Embrace Young Again Club Protocols.
  3. Ask for help and be open to new ideas.

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